SCHEMBL683043

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2136949	1.00	PDE4A (0.43)	PDE4APDE4BSLC5A7ATMCHRM4
	SCHEMBL682747	0.91	PDE4B (0.44)	PDE4APDE4BSLC5A7PDE4CPDE4D
	SCHEMBL2140445	0.91	PDE4B (0.44)	PDE4APDE4BSLC5A7PDE4CPDE4D
	SCHEMBL2142632	0.90	PDE4A (0.51)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL683369	0.90	PDE4A (0.51)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL877074	0.90	CYP3A4 (0.43)	PDE4APDE4BSLC5A7CHRM4PDE4C
	SCHEMBL877075	0.90	CYP3A4 (0.43)	PDE4APDE4BSLC5A7CHRM4PDE4C
	SCHEMBL2138265	0.89	PDE4A (0.50)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL681959	0.89	PDE4A (0.50)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL682749	0.88	PDE4B (0.46)	PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.