SCHEMBL6827494

SCHEMBL6827494

CC(C)(C)c1cc(C(C)(C)C)c([PH](O)(O)O)c(C(C)(C)C)c1.CCCCC(CC)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.36
NR5A1 Q13285 1/20 0.36
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2793568 0.85 NR5A2 (0.47) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
SCHEMBL31298935 0.84 NR5A2 (0.33) NR5A2NR5A1
SCHEMBL727872 0.82 NR5A2 (0.44) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
Phosphoric Acid SCHEMBL2954109 0.80 NR5A2 (0.48) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
SCHEMBL2951542 0.79 NR5A2 (0.36) NR5A2NR5A1
SCHEMBL769354 0.77 NR5A2 (0.38) NR5A2NR5A1
SCHEMBL7640191 0.76 GABRA1 (0.44) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
SCHEMBL2951541 0.73 NR5A2 (0.42) NR5A2NR5A1CYP1A2CYP3A4CYP2C9
SCHEMBL2954106 0.72 NR5A2 (0.44) NR5A2NR5A1
SCHEMBL2951546 0.72 NR5A2 (0.32) NR5A2NR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6773624-B2 REACTING GLYCOL SUCH AS PENTAERYTHRITOL WITH PHOSPHORUS TRIHALIDE TO PRODUCE HALO PHOSPHITE ESTER OF GLYCOL, REACTING PRODUCT WITH A PHENOL, REACTING SECOND PRODUCTS COMPRISING ORGANIC PHOSPHITE AND HALO PHOSPHITE WITH METAL PHENOLATE CROMPTON CORPORATION 2004-08-10 US disclosed