Serine

Serine

SCHEMBL6827952

N[C@@H](CC(C(=O)O)C(=O)O)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.60

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 5/20 0.60
SLC7A5 Q01650 1/20 0.52
SLC1A3 P43003 5/20 0.46
SLC1A2 P43004 5/20 0.46
ENPEP Q07075 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
GRIK1 P39086 4/20 0.43
GRIK2 Q13002 4/20 0.43
GGT1 P19440 2/20 0.43
GRM1 Q13255 1/20 0.43
GRM2 Q14416 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445471 0.89 SLC7A5 (0.62) SLC1A1SLC7A5SLC1A3SLC1A2ENPEP
SCHEMBL148584 0.89 SLC7A5 (0.62) SLC1A1SLC7A5SLC1A3SLC1A2ENPEP
SCHEMBL39093 0.89 SLC7A5 (0.62) SLC1A1SLC7A5SLC1A3SLC1A2ENPEP
SCHEMBL4303994 0.89 SLC7A5 (0.62) SLC1A1SLC7A5SLC1A3SLC1A2ENPEP
Serine SCHEMBL6929773 0.87 SLC1A1 (0.59) SLC1A1SLC7A5SLC1A3SLC1A2PTGS1
Serine SCHEMBL6520912 0.87 SLC1A1 (0.59) SLC1A1SLC7A5SLC1A3SLC1A2PTGS1
(D)-Serine SCHEMBL6660617 0.87 SLC1A1 (0.59) SLC1A1SLC7A5SLC1A3SLC1A2PTGS1
Serine SCHEMBL4455818 0.87 SLC1A1 (0.59) SLC1A1SLC7A5SLC1A3SLC1A2PTGS1
Serine SCHEMBL1332181 0.87
(D)-Serine SCHEMBL6038168 0.87 SLC1A1 (0.59) SLC1A1SLC7A5SLC1A3SLC1A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4534881-A Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives UNIVERSITY OF SOUTH ALABAMA (US) 1985-08-13 US claimed
WO-2004076425-A1 IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS CARNEGIE MELLON UNIVERSITY (US) 2004-09-10 WO disclosed