Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069592 | 0.83 | POLB (0.41) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL17318733 | 0.82 | POLB (0.46) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL30892255 | 0.82 | POLB (0.46) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL16048561 | 0.81 | POLB (0.45) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL17148693 | 0.78 | TSHR (0.41) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL31573601 | 0.77 | ALDH1A1 (0.51) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL21836913 | 0.77 | ALDH1A1 (0.51) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL18786805 | 0.77 | HPGD (0.47) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL18857938 | 0.75 | POLB (0.49) | POLBALDH1A1GAAKDM4EHPGD | |
| SCHEMBL22833407 | 0.75 | TSHR (0.44) | POLBALDH1A1GAAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |