Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969546 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL5544778 | 0.81 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL3494573 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL6828054 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10TDP1CSNK2A1 | |
| SCHEMBL13214335 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL1609214 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL7132765 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10TDP1MEN1 | |
| SCHEMBL3442549 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL14509736 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNA | |
| SCHEMBL269781 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10TDP1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |