Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206455 | 0.98 | FAAH (0.49) | FAAHCNR1CNR2HDAC1HDAC2 | |
| Butane SCHEMBL8404111 | 0.96 | FAAH (0.47) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL905444 | 0.87 | FAAH (0.53) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL905430 | 0.87 | FAAH (0.53) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL905443 | 0.87 | FAAH (0.53) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL5467177 | 0.86 | FAAH (0.58) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL4445232 | 0.86 | FAAH (0.58) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL6828062 | 0.85 | FAAH (0.66) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL8506456 | 0.83 | FAAH (0.69) | FAAHCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL28507255 | 0.83 | FAAH (0.69) | FAAHCNR1CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |