Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 1.00 |
| ▸ | ESR1 | P03372 | 16/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828285 | 0.79 | ESR2 (0.68) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6828387 | 0.78 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6828323 | 0.77 | ESR2 (1.00) | ESR2ESR1CSNK2A1 | |
| SCHEMBL10627951 | 0.75 | MAOB (0.71) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6926052 | 0.72 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL26766942 | 0.70 | ESR2 (0.66) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30629209 | 0.70 | ESR2 (0.66) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL15346134 | 0.70 | ATP1A1 (0.64) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6830519 | 0.70 | ESR2 (0.59) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6828097 | 0.70 | ESR2 (1.00) | ESR2ESR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |