Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828790 | 0.86 | PDE2A (0.56) | PDE2APKMNPSR1RXFP1PKLR | |
| SCHEMBL29853479 | 0.82 | PDE2A (0.65) | PDE2APKMNPSR1RXFP1PKLR | |
| SCHEMBL26768454 | 0.82 | PDE2A (0.65) | PDE2APKMNPSR1RXFP1PKLR | |
| SCHEMBL26766572 | 0.75 | PDE2A (0.63) | PDE2ANPSR1RXFP1PKLRMAPT | |
| SCHEMBL26768511 | 0.75 | PDE2A (0.63) | PDE2ANPSR1RXFP1PKLRMAPT | |
| SCHEMBL4929370 | 0.74 | CA9 (0.61) | RXFP1MAPTALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL27218950 | 0.74 | PDE2A (0.61) | PDE2ANPSR1RXFP1PKLRMAPT | |
| SCHEMBL290035 | 0.74 | MAPT (0.47) | MAPTALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL8945532 | 0.73 | KDM4E (0.40) | MAPTALDH1A1KDM4EPOLBMAOB | |
| SCHEMBL28644263 | 0.72 | KDM4E (0.57) | NPSR1MAPTALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |