Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945543 | 0.88 | ALDH1A1 (0.40) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL7796860 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1GAAMAPTHSD17B3 | |
| SCHEMBL6828193 | 0.73 | PDE2A (0.53) | KDM4EALDH1A1ALOX5GAAMAPT | |
| SCHEMBL4929370 | 0.71 | CA9 (0.61) | KDM4EALDH1A1GAAMAPTCA2 | |
| SCHEMBL3164161 | 0.70 | CA12 (0.48) | KDM4EALDH1A1GAAMAPTCA2 | |
| SCHEMBL5904495 | 0.66 | CA12 (0.68) | KDM4EALDH1A1GAAMAPTBACE1 | |
| SCHEMBL11426446 | 0.65 | AHR (0.53) | KDM4EALDH1A1MAOB | |
| SCHEMBL28644263 | 0.63 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTHSD17B3 | |
| SCHEMBL5658301 | 0.61 | PKM (0.50) | KDM4EALDH1A1 | |
| SCHEMBL4831773 | 0.61 | HSD17B3 (0.57) | KDM4EALDH1A1GAAMAPTHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |