SCHEMBL6828249

SCHEMBL6828249

NS(=O)(=O)C1NCCCN1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2705752 0.69
SCHEMBL28056778 0.69
SCHEMBL490278 0.63
Sulfamide SCHEMBL1647073 0.62 APLNR (0.39) APLNR
Sulfamide SCHEMBL27856392 0.61
SCHEMBL25040341 0.59 APLNR (0.36) APLNR
SCHEMBL20762013 0.59 APLNR (0.36) APLNR
SCHEMBL3888918 0.59
SCHEMBL6056260 0.59
Sulfamide SCHEMBL4141697 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004030629-A2 NOVEL NEUROKININ ANTAGONISTS AND METHODS OF USE THEREOF PREDIX PHARMACEUTICALS (US) 2004-04-15 WO disclosed