Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.52 |
| ▸ | MMP14 | P50281 | 9/20 | 0.52 |
| ▸ | MMP12 | P39900 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828257 | 1.00 | MMP13 (0.52) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL940503 | 0.83 | MMP13 (0.58) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL943926 | 0.80 | MMP13 (0.72) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL941841 | 0.80 | MMP13 (0.72) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL8233841 | 0.80 | MMP13 (0.72) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL944081 | 0.80 | MMP13 (0.72) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL941319 | 0.79 | MMP13 (0.62) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL942429 | 0.79 | MMP13 (0.67) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL941054 | 0.78 | MMP13 (0.73) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL6920418 | 0.77 | MMP13 (0.42) | MMP13MMP14MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024718-A1 | IMIDAZOLIDINEDIONE-DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | claimed |
| WO-2004024718-A1 | IMIDAZOLIDINEDIONE-DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |