Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 17/20 | 1.00 |
| ▸ | ESR1 | P03372 | 13/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828759 | 0.87 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6926041 | 0.81 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6926052 | 0.74 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6828387 | 0.71 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6828242 | 0.71 | ESR2 (0.89) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825403 | 0.71 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL3766383 | 0.71 | KDM4E (0.74) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6828141 | 0.71 | ESR2 (0.85) | ESR2ESR1 | |
| SCHEMBL7984298 | 0.69 | ESR2 (0.75) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL11056055 | 0.69 | KDM4E (0.59) | ESR2ESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |