Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LDHB | P07195 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040690 | 0.82 | TTR (0.48) | TTRDPP4LDHALDHBAKR1C2 | |
| SCHEMBL1882963 | 0.81 | DPP4 (0.47) | TTRDPP4LDHALDHBAKR1C2 | |
| SCHEMBL20233406 | 0.79 | DPP4 (0.52) | TTRDPP4AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL29613155 | 0.77 | DPP4 (0.50) | TTRDPP4AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL17318738 | 0.77 | DPP4 (0.50) | TTRDPP4AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL24727674 | 0.76 | HSD17B10 (0.40) | TTRALDH1A1HSD17B10MEN1GAA | |
| SCHEMBL28296608 | 0.75 | DPP4 (0.52) | TTRDPP4AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL2787863 | 0.75 | DPP4 (0.57) | TTRDPP4LDHALDHBAKR1C2 | |
| SCHEMBL31643481 | 0.73 | LDHA (0.43) | TTRDPP4LDHALDHBAKR1C2 | |
| SCHEMBL28820922 | 0.72 | DPP4 (0.39) | TTRDPP4AKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |