Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | CTSL | P07711 | 9/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710241 | 0.86 | CAPN1 (0.61) | CTSKCTSLCAPN1CTSSHTRA1 | |
| Hydrochloric Acid SCHEMBL6828093 | 0.85 | CAPN1 (0.60) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL8710235 | 0.79 | CAPN1 (0.60) | CTSKCTSLCAPN1CTSSHTRA1 | |
| Hydrochloric Acid SCHEMBL6828092 | 0.78 | CAPN1 (0.59) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL6828393 | 0.78 | CAPN1 (0.63) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL6828120 | 0.78 | CAPN1 (0.63) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL6825605 | 0.78 | CAPN1 (0.63) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL8916002 | 0.77 | CAPN1 (0.62) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL6828119 | 0.77 | CAPN1 (0.62) | CTSKCTSLCAPN1CTSSHTRA1 | |
| SCHEMBL8703908 | 0.76 | CAPN1 (0.56) | CTSKCTSLCAPN1CASP1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389624-A1 | Phosphorous-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| US-5639732-A | FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT | CEPHALON, INC. (US) | 1997-06-17 | — | — | US | disclosed |