SCHEMBL6828307

SCHEMBL6828307

CC(C)(C)OC(=O)CNc1ccc(N2CC(CN)OC2=O)cc1F

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.47
MAOA P21397 5/20 0.47
CALML3 P27482 3/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47
F10 P00742 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792784 1.00 MAOB (0.47) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6922622 0.88 MAOA (0.63) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6922619 0.88 MAOA (0.63) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6826425 0.87 MAOB (0.44) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6826301 0.87 MAOB (0.52) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6826300 0.87 MAOB (0.52) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6796171 0.87 MAOB (0.48) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6826232 0.86 MAOB (0.44) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6828306 0.86 F10 (0.43) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6826545 0.85 F10 (0.51) MAOBMAOACALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004101552-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) 2004-11-25 WO disclosed