SCHEMBL6828358

SCHEMBL6828358

COc1ccc(-c2sc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(OC4CCN(C)C4)c3)cc2Cl)cc1F

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.59
PI4KB Q9UBF8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825905 1.00 UTS2R (0.59) UTS2RPI4KB
SCHEMBL6828435 0.93 UTS2R (0.59) UTS2RPI4KB
SCHEMBL6828437 0.93 UTS2R (0.59) UTS2RPI4KB
SCHEMBL6828914 0.92 UTS2R (0.58) UTS2RPI4KB
SCHEMBL6828911 0.92 UTS2R (0.58) UTS2RPI4KB
SCHEMBL6830946 0.89 UTS2R (0.55) UTS2RPI4KB
SCHEMBL6830950 0.89 UTS2R (0.55) UTS2RPI4KB
SCHEMBL6828664 0.88 UTS2R (0.57) UTS2R
SCHEMBL6828662 0.88 UTS2R (0.57) UTS2R
SCHEMBL6828687 0.88 UTS2R (0.61) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed