Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 1.00 |
| ▸ | ESR1 | P03372 | 14/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828110 | 0.83 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6829011 | 0.77 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL7823288 | 0.76 | SHBG (0.61) | ESR2ESR1 | |
| Hydrazine SCHEMBL28219088 | 0.75 | ESR1 (0.60) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL6825368 | 0.72 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6825648 | 0.72 | ESR2 (0.77) | ESR2ESR1 | |
| SCHEMBL22413393 | 0.72 | ESR2 (0.71) | ESR2ESR1 | |
| SCHEMBL6828720 | 0.71 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6828637 | 0.69 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL6828329 | 0.69 | ESR2 (0.67) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |