Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | YES1 | P07947 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828691 | 1.00 | UTS2R (0.53) | UTS2RSLC22A12PIM1FLT3KCNH2 | |
| SCHEMBL6829212 | 0.93 | UTS2R (0.50) | UTS2RSLC22A12PIM1FLT3KCNH2 | |
| SCHEMBL6829217 | 0.93 | UTS2R (0.50) | UTS2RSLC22A12PIM1FLT3KCNH2 | |
| SCHEMBL6828553 | 0.92 | UTS2R (0.55) | UTS2RMCHR1 | |
| SCHEMBL6828551 | 0.92 | UTS2R (0.55) | UTS2RMCHR1 | |
| SCHEMBL6825907 | 0.90 | UTS2R (0.57) | UTS2R | |
| SCHEMBL6825909 | 0.90 | UTS2R (0.57) | UTS2R | |
| SCHEMBL6829204 | 0.90 | UTS2R (0.54) | UTS2R | |
| SCHEMBL6829210 | 0.90 | UTS2R (0.54) | UTS2R | |
| SCHEMBL6828309 | 0.88 | UTS2R (0.52) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043368-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |