SCHEMBL6828746

SCHEMBL6828746

CN1CC[C@@H](Oc2cc(NS(=O)(=O)c3cc(-c4ccccc4N)c(Cl)s3)ccc2C(F)(F)F)C1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 16/20 0.55
SCD O00767 2/20 0.36
FFAR4 Q5NUL3 2/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828751 1.00 UTS2R (0.55) UTS2RSCDFFAR4FFAR1
SCHEMBL6826104 0.93 UTS2R (0.57) UTS2RSCD
SCHEMBL6826102 0.93 UTS2R (0.57) UTS2RSCD
SCHEMBL8338931 0.92 UTS2R (0.57) UTS2R
SCHEMBL8338633 0.91 UTS2R (0.62) UTS2R
SCHEMBL8343459 0.90 UTS2R (0.62) UTS2RFFAR4FFAR1
SCHEMBL6828350 0.88 UTS2R (0.56) UTS2R
SCHEMBL6828716 0.88 UTS2R (0.54) UTS2R
SCHEMBL6828714 0.88 UTS2R (0.54) UTS2R
SCHEMBL6828865 0.87 UTS2R (0.52) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed