Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 15/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826489 | 0.85 | TERT (0.68) | TERTALDH1A1MEN1KMT2A | |
| SCHEMBL6828814 | 0.83 | TERT (1.00) | TERTALDH1A1MEN1KMT2A | |
| SCHEMBL6828762 | 0.76 | TERT (1.00) | TERTALDH1A1MEN1KMT2A | |
| SCHEMBL6829046 | 0.74 | TERT (1.00) | TERT | |
| SCHEMBL6831258 | 0.74 | TERT (1.00) | TERTALDH1A1MEN1KMT2A | |
| SCHEMBL6826433 | 0.73 | TERT (1.00) | TERT | |
| SCHEMBL6831125 | 0.72 | TERT (1.00) | TERTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL6826112 | 0.72 | TERT (1.00) | TERTKMT2A | |
| SCHEMBL6922934 | 0.72 | TERT (1.00) | TERTALDH1A1 | |
| SCHEMBL6829690 | 0.72 | TERT (1.00) | TERTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |