Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646553 | 0.81 | MAPT (0.56) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL1699147 | 0.80 | ALDH1A1 (0.56) | KCNK3KCNK9KMT2AIDO1TDO2 | |
| SCHEMBL6645352 | 0.80 | MAPT (0.57) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL6646478 | 0.77 | KCNK3 (0.45) | KCNK3KCNK9NPC1NFKB1RAB9A | |
| SCHEMBL2772492 | 0.77 | IDO1 (0.51) | KCNK3KCNK9L3MBTL1MEN1KMT2A | |
| SCHEMBL29370483 | 0.77 | IDO1 (0.61) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL6645872 | 0.76 | MELK (0.48) | KCNK3KCNK9NPC1NFKB1RAB9A | |
| SCHEMBL6643134 | 0.76 | HTT (0.50) | KCNK3KCNK9NPC1RAB9AL3MBTL1 | |
| SCHEMBL20215156 | 0.75 | IDO1 (0.49) | KCNK3KCNK9KMT2AIDO1TDO2 | |
| SCHEMBL20215155 | 0.75 | IDO1 (0.49) | KCNK3KCNK9KMT2AIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |