Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829320 | 0.84 | MRGPRX4 (0.64) | MRGPRX4TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL6619558 | 0.81 | MRGPRX4 (0.56) | MRGPRX4L3MBTL1TDP1RAB9AALDH1A1 | |
| SCHEMBL16812822 | 0.77 | MRGPRX4 (0.57) | MRGPRX4L3MBTL1TDP1RAB9AALDH1A1 | |
| SCHEMBL6829550 | 0.76 | MRGPRX4 (0.54) | MRGPRX4L3MBTL1RAB9AALDH1A1MEN1 | |
| SCHEMBL7129725 | 0.76 | MRGPRX4 (0.54) | MRGPRX4L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL6826427 | 0.75 | MRGPRX4 (0.56) | MRGPRX4L3MBTL1TDP1RAB9AALDH1A1 | |
| SCHEMBL22480846 | 0.75 | MRGPRX4 (1.00) | MRGPRX4TDP1RAB9AKMT2AMAPT | |
| SCHEMBL13735841 | 0.75 | MRGPRX4 (0.65) | MRGPRX4L3MBTL1TDP1ALDH1A1KMT2A | |
| SCHEMBL6831135 | 0.74 | MRGPRX4 (0.55) | MRGPRX4L3MBTL1TDP1RAB9AALDH1A1 | |
| SCHEMBL7128455 | 0.74 | MRGPRX4 (0.55) | MRGPRX4RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |