Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826427 | 0.88 | MRGPRX4 (0.56) | MRGPRX4FFAR1TP53MAPTHDAC4 | |
| SCHEMBL6829566 | 0.86 | MRGPRX4 (0.54) | MRGPRX4FFAR1TP53MAOBMAPT | |
| SCHEMBL6619558 | 0.85 | MRGPRX4 (0.56) | MRGPRX4TP53MAPTNR4A2NPSR1 | |
| SCHEMBL7131595 | 0.85 | MRGPRX4 (0.57) | MRGPRX4TP53MAOBMAPTHDAC4 | |
| SCHEMBL6829631 | 0.83 | RAB9A (0.57) | MRGPRX4FFAR1MAPTHDAC4HDAC6 | |
| SCHEMBL6831135 | 0.81 | MRGPRX4 (0.55) | MRGPRX4TP53MAPTHDAC4HDAC6 | |
| SCHEMBL6828653 | 0.80 | MRGPRX4 (0.64) | MRGPRX4TP53LMNAALDH1A1MEN1 | |
| SCHEMBL16812822 | 0.78 | MRGPRX4 (0.57) | MRGPRX4TP53MAPTHDAC4HDAC6 | |
| SCHEMBL7128455 | 0.78 | MRGPRX4 (0.55) | MRGPRX4TP53MAOBLMNANPC1 | |
| SCHEMBL7129725 | 0.77 | MRGPRX4 (0.54) | MRGPRX4FFAR1MAOBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |