Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.63 |
| ▸ | TK2 | O00142 | 3/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758892 | 0.90 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2582684 | 0.90 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL8369203 | 0.89 | PYGM (0.65) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL20550037 | 0.88 | PYGM (0.49) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21458099 | 0.88 | PYGM (0.52) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL3420804 | 0.88 | PYGM (0.61) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL6882436 | 0.86 | PYGM (0.61) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL6530419 | 0.86 | PYGM (0.61) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL216335 | 0.86 | PYGM (0.61) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10644978 | 0.85 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |