Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | CCR4 | P51679 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MYLK | Q15746 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392563 | 0.87 | HSD11B1 (0.50) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5830655 | 0.85 | HSD11B1 (0.50) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5831586 | 0.85 | HSD11B1 (0.50) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5830922 | 0.84 | HSD11B1 (0.46) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL6623269 | 0.84 | HSD11B1 (0.45) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5404821 | 0.83 | HSD11B1 (0.53) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5830828 | 0.83 | HSD11B1 (0.48) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5831440 | 0.82 | HSD11B1 (0.47) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5831031 | 0.82 | HSD11B1 (0.47) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB | |
| SCHEMBL5831141 | 0.82 | HSD11B1 (0.46) | HSD11B1HSD17B1HSD17B2SLC40A1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113310-A1 | USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |