SCHEMBL68294

SCHEMBL68294

O=C(O)c1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.68
CASP1 P29466 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
SRD5A2 P31213 2/20 0.56
ALDH1A1 P00352 4/20 0.52
TTR P02766 1/20 0.52
KDM4E B2RXH2 2/20 0.52
PYGL P06737 2/20 0.50
MYC P01106 2/20 0.50
MAPT P10636 2/20 0.50
ALOX15 P16050 1/20 0.50
NR4A1 P22736 1/20 0.50
TP53 P04637 2/20 0.48
POLB P06746 2/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
GAA P10253 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30162746 1.00 TSHR (0.68) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
Hydrochloric Acid SCHEMBL943311 0.98 TSHR (0.65) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
Hydrochloric Acid SCHEMBL1681859 0.98 TSHR (0.65) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL15463360 0.90 TSHR (0.57) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL28610796 0.90 TSHR (0.57) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL2815245 0.89 TSHR (0.63) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL11876536 0.87 TSHR (0.72) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL29017300 0.87 TSHR (0.53) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL7868076 0.85 TSHR (0.59) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1
SCHEMBL15855876 0.85 TSHR (0.61) TSHRCASP1SMN1; SMN2SRD5A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2768 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651988-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS ExxonMobil Technology and Engineering Company (US) 2025-11-26 EP claimed
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
CN-116162254-B Preparation method and application of metal organic framework material 中国科学院上海应用物理研究所 2025-04-29 CN claimed
CN-119857380-A Gas separation membrane based on metal organic cage and preparation method and application thereof 天津大学 2025-04-22 CN claimed
CN-119715696-A Preparation method and application of In2O3-Co3O4 heterostructure material 中国科学院大连化学物理研究所 2025-03-28 CN claimed
US-20250050310-A1 METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) AND/OR VOLATILE ALCOHOLS ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2025-02-13 US claimed
CN-118812862-A Metal-organic framework and rare earth nanocrystalline composite material with thermal enhancement type fluorescence temperature measurement function and preparation method and application thereof 浙江大学杭州国际科创中心 2024-10-22 CN claimed
EP-4444461-A1 METAL ORGANIC FRAMEWORKS FOR THE SELECTIVE CAPTURE OF VOLATIL ORGANIC COMPOUNDS COMPRISING CARBOXYLIC ACID FUNCTIONAL GROUP(S) AND/OR VOLATILE ALCOHOLS Centre National de la Recherche Scientifique (FR) 2024-10-16 EP claimed
US-20240254148-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-08-01 US claimed
WO-2024155562-A1 METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS ExxonMobil Technology and Engineering Company (US) 2024-07-25 WO claimed
US-4726998-A LIQUID CRYSTAL POLYMER SUBSTRATE, MAGNETIC LAYER POLYPLASTICS CO., LTD. (JP) 1988-02-23 US claimed
US-4645802-A MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1987-02-24 US claimed
US-4554206-A Polyester hot-melt adhesives EASTMAN KODAK COMPANY (US) 1985-11-19 US claimed
US-4468510-A FILMS, FIBERS, MOLDING PLASTICS, LOW GAS PERMEABILITY EASTMAN KODAK COMPANY (US) 1984-08-28 US claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed
EP-0011640-B1 POLYESTERS OF 4-CARBOXYBENZENEPROPIONIC ACID EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-04-27 EP claimed
EP-0011640-A4 POLYESTERS OF 4-CARBOXYBENZENEPROPIONIC ACID. EASTMAN KODAK CO (US) 1980-09-29 EP claimed
EP-0011640-A1 POLYESTERS OF 4-CARBOXYBENZENEPROPIONIC ACID. EASTMAN KODAK CO (US) 1980-06-11 EP claimed
WO-1979001030-A1 POLYESTERS OF 4-CARBOXYBENZENEPROPIONIC ACID EASTMAN KODAK CO (US) 1979-11-29 WO claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed