Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792873 | 0.88 | FLT1 (0.46) | TSHRCASP1SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL2560422 | 0.85 | XDH (0.56) | TSHRCASP1SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL68294 | 0.85 | TSHR (0.68) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| SCHEMBL30162746 | 0.85 | TSHR (0.68) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| SCHEMBL19200201 | 0.85 | TSHR (0.55) | TSHRCASP1SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL6240701 | 0.84 | TSHR (0.61) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| SCHEMBL2815245 | 0.83 | TSHR (0.63) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| Hydrochloric Acid SCHEMBL943311 | 0.83 | TSHR (0.65) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| Hydrochloric Acid SCHEMBL1681859 | 0.83 | TSHR (0.65) | TSHRCASP1SMN1; SMN2MYCNR4A1 | |
| SCHEMBL2556733 | 0.81 | EIF4E (0.53) | TSHRCASP1SMN1; SMN2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396159-A | Synthesis method of 2,2' -biphenyl dicarboxylic acid compound | 湖南大学 | 2023-07-07 | — | — | CN | disclosed |
| EP-3013819-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | Merial, Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014206911-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| EP-1063982-A2 | ANTAGONISTS FOR TREATMENT OF CD11/CD18 ADHESION RECEPTOR MEDIATED DISORDERS | Genentech, Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999049856-A2 | ANTAGONISTS FOR TREATMENT OF CD11/CD18 ADHESION RECEPTOR MEDIATED DISORDERS | GENENTECH, INC. (US) | 1999-10-07 | — | — | WO | disclosed |