Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.75 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38650720 | 1.00 | NFE2L2 (0.75) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL2234105 | 0.86 | NFE2L2 (1.00) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL15353049 | 0.81 | — | — | |
| SCHEMBL11209913 | 0.80 | NFE2L2 (0.43) | NFE2L2NFKB1MAOB | |
| SCHEMBL575116 | 0.78 | — | — | |
| SCHEMBL14162953 | 0.77 | NFE2L2 (0.71) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL6804693 | 0.77 | NFE2L2 (0.71) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL2089367 | 0.77 | NFE2L2 (0.71) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL2089369 | 0.77 | NFE2L2 (0.71) | NFE2L2RELANPC1PKMNFKB1 | |
| SCHEMBL3434176 | 0.77 | NFE2L2 (0.71) | NFE2L2RELANPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113511972-A | (E) Preparation method of (E) -4-aryl-2, 2-difluoro-3-butenoic acid derivative | 昆明理工大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-100389113-C | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-1630650-A | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2005-06-22 | — | — | CN | disclosed |
| EP-1159265-B1 | C-16 UNSATURATED FP-SELECTIVE PROSTAGLANDINS ANALOGS | UNIV DUKE (US) | 2004-11-24 | — | — | EP | disclosed |
| US-6451859-B1 | C16 unsaturated FP-selective prostaglandins analogs | THE PROCTER & GAMBLE COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-1159265-A1 | C-16 UNSATURATED FP-SELECTIVE PROSTAGLANDINS ANALOGS | THE PROCTER & GAMBLE COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051979-A1 | C16 UNSATURATED FP-SELECTIVE PROSTAGLANDINS ANALOGS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |