Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829590 | 1.00 | L3MBTL1 (0.45) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6489530 | 0.89 | MAPT (0.44) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7067283 | 0.84 | MCL1 (0.42) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7067278 | 0.84 | MCL1 (0.42) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6487855 | 0.79 | MAPT (0.45) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6501580 | 0.78 | MCL1 (0.47) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7316016 | 0.76 | MCL1 (0.45) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7131566 | 0.76 | KMT2A (0.44) | L3MBTL1MAPTALDH1A1NPC1LMNA | |
| SCHEMBL6488315 | 0.75 | MAPT (0.42) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10176161 | 0.75 | MAPT (0.62) | L3MBTL1MAPTALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |