Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486478 | 0.84 | HSP90AB1 (0.50) | HSP90AB1TSHRCYP1A2HSP90AA1LMNA | |
| SCHEMBL741180 | 0.84 | HSP90AB1 (0.50) | HSP90AB1TSHRCYP1A2HSP90AA1LMNA | |
| SCHEMBL763785 | 0.79 | HRH4 (0.37) | HSP90AB1HSP90AA1MAPTNPC1HRH3 | |
| SCHEMBL151114 | 0.77 | — | — | |
| SCHEMBL13744682 | 0.77 | TSHR (0.59) | HSP90AB1TSHRCYP1A2HSP90AA1LMNA | |
| SCHEMBL21711151 | 0.76 | CYP1A2 (0.48) | HSP90AB1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL191457 | 0.76 | KMT2A (0.59) | HSP90AB1CYP1A2CYP2C19HSP90AA1LMNA | |
| SCHEMBL7568606 | 0.75 | HSP90AB1 (0.55) | HSP90AB1TSHRCYP1A2HSP90AA1LMNA | |
| SCHEMBL7568049 | 0.75 | HSP90AB1 (0.55) | HSP90AB1TSHRCYP1A2CYP2C19HSP90AA1 | |
| Ammonia Solution, Strong SCHEMBL20919221 | 0.75 | HSP90AA1 (0.56) | HSP90AB1TSHRCYP1A2CYP2C19HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463483-A1 | NEW COMPOSITION | Ponsus Pharma AB (SE) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003055454-A1 | NEW COMPOSITION | PONSUS PHARMA AB (SE) | 2003-07-10 | — | — | WO | disclosed |