SCHEMBL683040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2137585	1.00	CCR1 (0.38)	CCR1P2RX7ALKHIF1APDE4B
	SCHEMBL682752	0.91	PDE4B (0.41)	PDE4B
	SCHEMBL2136806	0.91	PDE4B (0.41)	PDE4B
	SCHEMBL878473	0.84	PDE4D (0.43)	CCR1PDE4B
	SCHEMBL681944	0.84	PDE4D (0.43)	CCR1PDE4B
	SCHEMBL873918	0.84	PDE4B (0.36)	PDE4BDPP4
	SCHEMBL873919	0.84	HTR1A (0.39)	PDE4BDPP4
	SCHEMBL2137400	0.83	PDE4B (0.41)	PDE4BACACB
	SCHEMBL683367	0.83	PDE4B (0.41)	PDE4BACACB
	SCHEMBL683355	0.83	NR1H2 (0.40)	CCR1ALKALDH1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.