SCHEMBL683078

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL874976	1.00	PDE4D (0.51)	PDE4DPDE4BPDE4APDE4CPDE1C
	SCHEMBL683079	0.92	NR1H2 (0.43)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL873460	0.92	NR1H2 (0.43)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL878172	0.89	PDE4B (0.48)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL682001	0.89	PDE4D (0.50)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL878173	0.89	PDE4B (0.48)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL874477	0.89	PDE4D (0.50)	PDE4DPDE4BPDE4APDE4CNR1H2
	SCHEMBL2138568	0.88	PDE4B (0.49)	PDE4DPDE4BPDE4APDE4CPDE1C
	SCHEMBL683038	0.88	PDE4B (0.49)	PDE4DPDE4BPDE4APDE4CPDE1C
	SCHEMBL882566	0.88	NR1H2 (0.43)	NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.