SCHEMBL873460

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL683079	1.00	NR1H2 (0.43)	NR1H2NR1H3DPP4DPP7PDE4A
	SCHEMBL882566	0.95	NR1H2 (0.43)	NR1H2NR1H3DPP4DPP7CHRM4
	SCHEMBL875123	0.95	NR1H2 (0.43)	NR1H2NR1H3DPP4DPP7CHRM4
	SCHEMBL878172	0.93	PDE4B (0.48)	NR1H2NR1H3DPP4DPP7PDE4A
	SCHEMBL878173	0.93	PDE4B (0.48)	NR1H2NR1H3DPP4DPP7PDE4A
	SCHEMBL682001	0.93	PDE4D (0.50)	NR1H2NR1H3DPP4DPP7PDE4A
	SCHEMBL874477	0.93	PDE4D (0.50)	NR1H2NR1H3DPP4DPP7PDE4A
	SCHEMBL683078	0.92	PDE4D (0.51)	NR1H2NR1H3PDE4APDE4BPDE4C
	SCHEMBL874976	0.92	PDE4D (0.51)	NR1H2NR1H3PDE4APDE4BPDE4C
	SCHEMBL2142877	0.88	NR1H2 (0.43)	NR1H2NR1H3DPP4DPP7CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.