Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.83 |
| ▸ | KDR | P35968 | 15/20 | 0.83 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | YES1 | P07947 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | CSK | P41240 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831114 | 0.97 | SRC (0.81) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6831726 | 0.90 | SRC (0.93) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6920379 | 0.85 | SRC (0.83) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6924560 | 0.85 | SRC (0.79) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6921967 | 0.83 | SRC (0.81) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6832867 | 0.82 | SRC (0.79) | SRCKDREGFR | |
| SCHEMBL6824096 | 0.81 | SRC (0.83) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6830881 | 0.80 | SRC (0.77) | SRCKDREGFR | |
| SCHEMBL4033880 | 0.80 | EGFR (0.85) | SRCKDREGFRLCKYES1 | |
| SCHEMBL6919929 | 0.78 | SRC (0.81) | SRCKDREGFRLCKYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004081000-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |