Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600104 | 0.87 | CYP2D6 (0.48) | PTPN1CYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL3859527 | 0.79 | GAA (0.61) | MCHR1CYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL3616464 | 0.79 | BIRC5 (0.54) | MCHR1CYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL11856053 | 0.76 | RAB9A (0.53) | CYP1A2CYP2D6MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28541885 | 0.73 | GAA (0.60) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL11233185 | 0.73 | KDM4E (0.65) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL1734232 | 0.73 | CYP2D6 (0.73) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL4041381 | 0.72 | KDM4E (0.59) | CYP1A2CYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL374223 | 0.72 | EBP (0.62) | MCHR1CYP1A2CYP2D6MAPTCHRNA7 | |
| SCHEMBL12521822 | 0.72 | KDM4E (0.50) | CYP1A2CYP2D6SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046118-A2 | 2-4-(DI-PHENYL-AMINO)-PYRIMIDINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |