Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995096 | 0.80 | KMT2A (0.71) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL6937981 | 0.80 | KMT2A (0.71) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL13073431 | 0.78 | KMT2A (0.85) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL19972744 | 0.78 | KMT2A (0.85) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL8268852 | 0.77 | KMT2A (0.56) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL6368964 | 0.75 | KMT2A (0.64) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL6240572 | 0.74 | KMT2A (0.70) | KMT2AMEN1CXCR3BLMPOLB | |
| Hydrochloric Acid SCHEMBL4786521 | 0.73 | KMT2A (0.73) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL27470508 | 0.72 | KMT2A (0.57) | KMT2AMEN1CXCR3BLMPOLB | |
| SCHEMBL14159523 | 0.71 | BLM (0.63) | KMT2AMEN1CXCR3BLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770656-B2 | NEURODEGENERATIVE DISORDERS; ANTIEPILEPTIC AND ANTIISCHEMIC AGENTS; INFERTILITY, CARDIOVASCULAR DISORDERS, RENAL HYPOXIA, HEPATITIS AND AIDS TREATMENT | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-08-03 | — | — | US | disclosed |