Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937981 | 1.00 | KMT2A (0.71) | KMT2AMEN1CXCR3HDAC8SMYD3 | |
| SCHEMBL19972744 | 0.82 | KMT2A (0.85) | KMT2AMEN1CXCR3HDAC8POLB | |
| SCHEMBL13073431 | 0.82 | KMT2A (0.85) | KMT2AMEN1CXCR3HDAC8POLB | |
| SCHEMBL7044762 | 0.81 | MAPT (0.54) | KMT2AMEN1 | |
| SCHEMBL6359841 | 0.80 | PKM (0.53) | KMT2AMEN1POLB | |
| SCHEMBL6831395 | 0.80 | KMT2A (0.59) | KMT2AMEN1CXCR3HDAC8SMYD3 | |
| SCHEMBL6368964 | 0.79 | KMT2A (0.64) | KMT2AMEN1CXCR3HDAC8SMYD3 | |
| SCHEMBL8268852 | 0.78 | KMT2A (0.56) | KMT2AMEN1CXCR3SMYD3POLB | |
| SCHEMBL6240572 | 0.78 | KMT2A (0.70) | KMT2AMEN1CXCR3HDAC8POLB | |
| SCHEMBL6428974 | 0.78 | OPRM1 (0.54) | KMT2AMEN1CXCR3SMYD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902781-A4 | PREPARATION OF (S)-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID T-BUTYLAMIDE | NSC TECHNOLOGIES LLC (US) | 2000-07-19 | — | — | EP | claimed |
| EP-0902781-A1 | PREPARATION OF (S)-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID T-BUTYLAMIDE | Monsanto Company (US) | 1999-03-24 | — | — | EP | claimed |
| WO-1997030976-A1 | PREPARATION OF (S)-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID T-BUTYLAMIDE | MONSANTO COMPANY (US) | 1997-08-28 | — | — | WO | claimed |