Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 9/20 | 0.57 |
| ▸ | KDR | P35968 | 8/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | MET | P08581 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669865 | 0.83 | KDR (0.69) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL6831453 | 0.80 | KDR (0.63) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL5638280 | 0.75 | KDR (0.78) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL25779633 | 0.75 | KDR (0.83) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL4669693 | 0.74 | KDR (0.73) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL4668929 | 0.74 | KDR (0.64) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL29366679 | 0.74 | KDR (1.00) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL29918224 | 0.74 | KDR (1.00) | AXLKDRPDGFRAFGFR2KIT | |
| SCHEMBL1249562 | 0.74 | KDR (1.00) | AXLKDRPDGFRAFGFR2KIT | |
| Hydrochloric Acid SCHEMBL4668966 | 0.74 | KDR (0.71) | AXLKDRPDGFRAFGFR2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1382604-A1 | QUINOLINE DERIVATIVE HAVING AZOLYL GROUP AND QUINAZOLINE DERIVATIVE | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-01-21 | — | — | EP | disclosed |