Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481096 | 0.88 | SCN9A (0.45) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3784682 | 0.85 | TRPV1 (0.46) | LMNAPOLB | |
| SCHEMBL9283981 | 0.83 | AAK1 (0.51) | ALDH1A1JAK2AAK1MAPTLMNA | |
| SCHEMBL9286086 | 0.83 | AAK1 (0.51) | ALDH1A1JAK2AAK1MAPTLMNA | |
| SCHEMBL3007581 | 0.80 | JAK2 (0.52) | JAK2AAK1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3007580 | 0.80 | JAK2 (0.52) | JAK2AAK1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL15020425 | 0.79 | HPGD (0.51) | ALDH1A1JAK2AAK1NPSR1MAPT | |
| SCHEMBL8347748 | 0.79 | PGR (0.53) | ALDH1A1SMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL31045386 | 0.78 | MAPT (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAL3MBTL1 | |
| SCHEMBL11903216 | 0.78 | HDAC1 (0.41) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074238-A1 | PHENETHYLAMINO SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |