Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL280428 | 0.98 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29628855 | 0.98 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Water SCHEMBL3636507 | 0.96 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL7799642 | 0.96 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Bromide SCHEMBL7761036 | 0.96 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Water SCHEMBL10356869 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Water SCHEMBL10356864 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29444130 | 0.94 | HPRT1 (0.58) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL2126075 | 0.94 | HPRT1 (0.58) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL30713692 | 0.94 | HPRT1 (0.58) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627360-A1 | SILICA NANOPARTICLES DOPED WITH MULTIPLE DYES FEATURING HIGHLY EFFICIENT ENERGY TRANSFER AND TUNABLE STOKES-SHIFT | Alma Mater Studiorum -Universita' di Bologna (IT) | 2013-08-21 | — | — | EP | claimed |
| WO-2012049657-A1 | SILICA NANOPARTICLES DOPED WITH MULTIPLE DYES FEATURING HIGHLY EFFICIENT ENERGY TRANSFER AND TUNABLE STOKES-SHIFT | ALMA MATER STUDIORUM UNIVERSITÀ DI BOLOGNA (IT) | 2012-04-19 | — | — | WO | claimed |
| WO-2024148293-A1 | CHARGED PI-CONJUGATED MOLECULES FOR THE TREATMENT OF MICROBIAL INFECTIONS | WILLIAM MARSH RICE UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2019217583-A1 | NEAR-INFRARED HARVESTING TRANSPARENT LUMINESCENT SOLAR CONCENTRATORS WITH ENGINEERED STOKES SHIFT | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2019-11-14 | — | — | WO | disclosed |
| US-6740128-B2 | BLEND CONTAINING ENAMINE AND ALKALINE MIXTURE OF ALDEHYDE AND PRIMARY AMINE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | disclosed |