Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | LAP3 | P28838 | 4/20 | 0.52 |
| ▸ | ANPEP | P15144 | 3/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.52 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.48 |
| ▸ | IL1RN | P18510 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580246 | 1.00 | CCR1 (0.54) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4065391 | 0.88 | ERAP2 (0.53) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4062972 | 0.86 | SLC1A3 (0.53) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4070006 | 0.85 | CCR1 (0.45) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL2675073 | 0.83 | CCR1 (0.57) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4071139 | 0.82 | HTR2A (0.52) | CCR1 | |
| SCHEMBL4067470 | 0.82 | CCR1 (0.44) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6167499 | 0.82 | CCR1 (0.57) | CCR1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4061788 | 0.81 | CCR1 (0.46) | CCR1ERAP2ERAP1IL1RNLNPEP | |
| SCHEMBL9076303 | 0.81 | CSNK1E (0.64) | LAP3ANPEPRNPEPDNPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | PFIZER INC | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | CCR1, CCR3, CCRL2 | CCR1 1/4885LAP3 2885/4885ANPEP 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.