Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372607 | 0.84 | NPSR1 (0.44) | NPSR1CA1CA2KMT2AMEN1 | |
| SCHEMBL1563099 | 0.80 | NPSR1 (0.58) | NPSR1CA1CA2KMT2AMEN1 | |
| SCHEMBL27451872 | 0.79 | NPSR1 (0.37) | NPSR1KMT2ATRPM8HTTALDH1A1 | |
| SCHEMBL402771 | 0.72 | NPSR1 (0.41) | NPSR1CA1CA2KMT2AMEN1 | |
| SCHEMBL28794245 | 0.72 | MTNR1A (0.36) | NPSR1KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9431613 | 0.71 | NAPRT (0.37) | NPSR1KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL12914594 | 0.70 | NPSR1 (0.61) | NPSR1CA1CA2KMT2AMEN1 | |
| SCHEMBL7521136 | 0.68 | — | — | |
| SCHEMBL27514959 | 0.68 | EGFR (0.39) | KMT2AMEN1HTTL3MBTL1TSHR | |
| SCHEMBL11788320 | 0.67 | PTGIR (0.34) | NPSR1CA1CA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |