SCHEMBL6832448

SCHEMBL6832448

CC=CC(=O)Oc1ccc(-c2ccccn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP19A1 P11511 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPC1 O15118 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
KMT2A Q03164 3/20 0.45
MAPT P10636 3/20 0.45
PKM P14618 2/20 0.45
RAB9A P51151 2/20 0.45
TP53 P04637 1/20 0.45
ABL1 P00519 2/20 0.43
BCR P11274 2/20 0.43
MEN1 O00255 2/20 0.41
TRPV1 Q8NER1 1/20 0.41
KDM4E B2RXH2 3/20 0.41
DHODH Q02127 1/20 0.41
ALDH1A1 P00352 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6590103 0.81 LMNA (0.57) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL13458077 0.80 LMNA (0.56) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL20577757 0.79 HSD17B10 (0.46) KMT2AMAPTRAB9AMEN1LMNA
SCHEMBL29177459 0.78 CYP1A2 (0.51) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL2959744 0.77 ELANE (0.57) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL18573395 0.76 MAPT (0.60) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL6842392 0.75 ELANE (0.56) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL4986100 0.75 ELANE (0.56) CYP2C9CYP1A2CYP2D6CYP19A1CYP2C19
SCHEMBL574100 0.75 KMT2A (0.50) KMT2AMAPTMEN1KDM4EALDH1A1
SCHEMBL574099 0.75 KMT2A (0.50) KMT2AMAPTMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1407501-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE Showa Denko K.K. (JP) 2004-04-14 EP disclosed
WO-2003001616-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2003-01-03 WO disclosed