Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832451 | 0.82 | CYP3A4 (0.52) | CYP3A4CYP19A1NQO2TNFRSF1APTGS2 | |
| SCHEMBL10135112 | 0.82 | CYP3A4 (0.45) | CYP3A4CYP19A1NQO2TNFRSF1APTGS2 | |
| SCHEMBL6832654 | 0.80 | CYP3A4 (0.49) | CYP3A4CYP19A1NQO2TNFRSF1APTGS2 | |
| SCHEMBL6832599 | 0.79 | CYP3A4 (0.43) | CYP3A4CYP19A1NQO2TNFRSF1APTGS2 | |
| SCHEMBL6832551 | 0.79 | CYP3A4 (0.49) | CYP3A4CYP19A1NQO2TNFRSF1ATUBB4A | |
| SCHEMBL6832521 | 0.78 | CYP3A4 (0.54) | CYP3A4CYP19A1NQO2TNFRSF1ATUBB4A | |
| SCHEMBL2130776 | 0.77 | CYP3A4 (0.53) | CYP3A4CYP19A1NQO2TNFRSF1ATUBB4A | |
| SCHEMBL6832649 | 0.77 | CYP3A4 (0.51) | CYP3A4CYP19A1NQO2TNFRSF1ATUBB4A | |
| SCHEMBL6765262 | 0.77 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL6832700 | 0.76 | CYP3A4 (0.48) | CYP3A4CYP19A1NQO2TNFRSF1ATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178547-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100158860-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | STEINER SANDRA | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158860-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | RFC1, RRP1B, RRBP1 | CYP3A4 978/4885CYP19A1 776/4885NQO2 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.