Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | CCR10 | P46092 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441423 | 0.86 | KMT2A (0.62) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL3807522 | 0.84 | KMT2A (0.51) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL10339231 | 0.83 | LMNA (0.50) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL9621330 | 0.83 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL9318067 | 0.81 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL10932608 | 0.81 | LMNA (0.43) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL294230 | 0.80 | LMNA (0.44) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL9406432 | 0.80 | LMNA (0.43) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL6236946 | 0.79 | KMT2A (0.42) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL7206704 | 0.79 | KMT2A (0.42) | KMT2ALMNATHRBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743925-B1 | FLUORINE RADIOTAGGED; DETECTION OF CANCER CELLS OR ISCHEMIC SITES OF CIRCULATORY ORGANS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2004-06-01 | — | — | US | disclosed |
| EP-1218351-A2 | NITROIMIDAZOLE DERIVATIVE AND DIAGNOSTIC IMAGING AGENT CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019799-A2 | NITROIMIDAZOLE DERIVATIVE AND DIAGNOSTIC IMAGING AGENT CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-03-22 | — | — | WO | disclosed |