⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683348 | 0.95 | PPARG (0.59) | — | |
| SCHEMBL684043 | 0.92 | AGTR2 (0.59) | — | |
| SCHEMBL9882910 | 0.92 | AGTR2 (0.55) | — | |
| SCHEMBL7019109 | 0.88 | AGTR2 (0.64) | — | |
| SCHEMBL18087887 | 0.86 | AGTR2 (0.59) | — | |
| SCHEMBL8543694 | 0.86 | AGTR2 (0.80) | — | |
| SCHEMBL18088504 | 0.85 | AGTR2 (0.56) | — | |
| SCHEMBL7017925 | 0.85 | AGTR2 (0.61) | — | |
| SCHEMBL7014433 | 0.85 | AGTR2 (0.63) | — | |
| SCHEMBL7018109 | 0.85 | AGTR2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |