Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 4/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599110 | 0.79 | KDM4E (0.38) | DYRK1AKDM4EADORA2AADORA1TTBK1 | |
| SCHEMBL19153637 | 0.78 | KDM4E (0.51) | DYRK1AKDM4EADORA2AADORA1TTBK1 | |
| SCHEMBL3767011 | 0.78 | KDM4E (0.37) | DYRK1AKDM4EADORA2AADORA1TTBK1 | |
| SCHEMBL12391478 | 0.75 | LRRK2 (0.40) | KDM4EADORA2AADORA1TTBK1TTBK2 | |
| SCHEMBL22701124 | 0.74 | KDM4E (0.35) | DYRK1AKDM4EADORA2AADORA1TTBK1 | |
| SCHEMBL21388537 | 0.74 | JAK3 (0.40) | KDM4EADORA2AADORA1TTBK1TTBK2 | |
| SCHEMBL18238494 | 0.74 | ADORA2A (0.40) | DYRK1AKDM4EADORA2AADORA1TTBK1 | |
| SCHEMBL102201 | 0.72 | TTBK1 (0.54) | DYRK1ATTBK1TTBK2AXLPRKCI | |
| SCHEMBL18332807 | 0.72 | CHEK1 (0.50) | CHEK1DYRK1AAURKA | |
| SCHEMBL20061392 | 0.71 | KDM4E (0.53) | KDM4EADORA2AADORA1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | GENELABS TECHNOLOGIES, INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | HAVCR2, PNP, NTPCR | CHEK1 1915/4885DYRK1A 4850/4885KDM4E 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.