Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.53 |
| ▸ | WEE2 | P0C1S8 | 1/20 | 0.53 |
| ▸ | WEE1 | P30291 | 1/20 | 0.53 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930676 | 0.96 | SRC (0.57) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6689932 | 0.89 | SRC (0.61) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6832341 | 0.86 | SRC (0.72) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6688317 | 0.85 | SRC (0.61) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6834092 | 0.83 | SRC (0.59) | SRCABL1BCREGFRERBB2 | |
| Hydrochloric Acid SCHEMBL19207239 | 0.81 | SRC (0.84) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6829234 | 0.81 | ENPP1 (0.52) | SRCEGFR | |
| SCHEMBL29618203 | 0.80 | SRC (0.85) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL2886333 | 0.80 | SRC (0.85) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6382930 | 0.78 | SRC (0.72) | SRCABL1BCREGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108703-A1 | PYRAZINYL 3-CYANOQUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |