Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832859 | 0.91 | MLLT1 (0.52) | DRD4F10MLLT1HRH4CCKBR | |
| SCHEMBL15506751 | 0.86 | DRD4 (0.65) | DRD4F10HRH4 | |
| SCHEMBL5260262 | 0.86 | F10 (0.59) | F10PYGLPYGM | |
| SCHEMBL5256019 | 0.84 | CCKBR (0.57) | MLLT1CCKBRCGASPYGLPYGM | |
| SCHEMBL27558367 | 0.84 | CCKBR (0.57) | MLLT1CCKBRCGASPYGLPYGM | |
| SCHEMBL29176327 | 0.84 | MLLT1 (0.61) | DRD4MLLT1HRH4 | |
| SCHEMBL6839437 | 0.83 | DRD4 (0.50) | DRD4F10MLLT1HRH4PYGL | |
| SCHEMBL5256902 | 0.83 | F10 (0.43) | DRD4F10MLLT1CCKBRCGAS | |
| SCHEMBL5255542 | 0.83 | KMT2A (0.55) | HRH4 | |
| SCHEMBL29176357 | 0.83 | MLLT1 (0.60) | DRD4MLLT1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759428-B2 | SUCH AS N-((1,2)-2-(((CYANO(CYCLOPROPYL)METHYL)AMINO)CARBONYL) CYCLOHEXYL)-1H-INDOLE-2-CARBOXAMIDE; CATHEPSIN K INHIBITORS | ROCHE PALO ALTO LLC | 2004-07-06 | — | — | US | disclosed |