SCHEMBL6834823

SCHEMBL6834823

COc1ccc([SiH2]c2ccc(OC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
ACHE P22303 1/20 0.60
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
ENPP2 Q13822 1/20 0.50
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849340 0.92 ACHE (0.75) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.80 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.80 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL5961824 0.80 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL12894663 0.78 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL22643597 0.78 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL13925529 0.75
SCHEMBL12464 0.75
SCHEMBL19182839 0.75 ACHE (1.00) CA1CA2CA7CA9CA12
SCHEMBL8428815 0.74 CA1 (0.52) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed
CN-107250166-B Modified conjugated diene polymer, method for producing same, rubber composition, and tire 旭化成株式会社 2021-09-24 CN disclosed
US-6753401-B1 DEHYDROGENATIVE POLYMERIZATION OF QUINONE AND/OR DIOL WITH TRIHYDROSILANE OR DIHYDROSILANE IN PRESENCE OF PALLADIUM-CONTAINING CATALYST; POLYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-06-22 US disclosed
EP-1234829-A1 SILICON-CONTAINING POLYMERS National Institute of Advanced Industrial Science and Technology (JP) 2002-08-28 EP disclosed